Yep, I swapped my X and Y axes on my LowRider v3, and edited the firmware accordingly, and the process included making it so my new Y axis could home to the new location (which is the opposite of how it homed when it was the X axis). This process was not difficult, and I’m glad I did it.
The whole process was discussed and documented here:
and the printed parts for the homing switch are available here: