There are a number of different possibilities depending on whether:
Y1 never really worked
Y1 is losing steps
Y1 worked in the past, but is unpowered now
You can tell if a stepper is unpowered by attempting to move the axis near the motor. If there is resistance, then the stepper is engaged.
If Y1 is powered but losing steps, then a mechanical issue, like loose grub screws on the connector between the stepper and lead screw, is the most likely source of the issue.
If Y1 worked in the past but is unpowered now, then I agree with Dreyfus that wiring is the most likely issue.
Given drag chains and flexing wires and connectors, it is possible for the motor to be disconnected at only certain router positions. If this is the case, there is a risk of blowing the stepper driver when the moving motor is disconnected. You might swap stepper drivers between Y1 with Y2 just to verify the stepper driver you are using for Y1 is still good.