Looking at the numbers here, I came pretty close with SKR Pro and el-cheapo TMC 2209 drivers using a 24V system. The only caveat here being that it’s with rotozip and not a 1.5-2x heavier VFD spindle.
- 200mm/s speeds on x/y - check
- 40mm/s on Z - check
- 1000mm/s^2 accel on x/y - check, I even tested up to 2k accel without a router attached
- Lifting 12lb of weight with the gantry - check
With 8bit board, the board froze whenever you tried to push past 50mm/s on x/y. My conclusion at the time was that 8bit boards are the limiting factor on raw movement speed so I binned my RAMPS 
With MPCNC speeds didn’t matter until I wanted to do 3D carving. That’s where the super-slow defaults on Z really hurt performance. For anything else, heck, the machine is not designed to actually cut at these speeds anyway.
For LR2 I had to lower the limits to 150mm/s because I was losing steps at 200mm/s. With a full sheet machine, travel speeds do make a difference especially with sensorless homing and a starting sequence that moves the gantry a few times back and forth in both directions to make sure that it doesn’t bind or catch on something mid cycle.
So yeah, I guess the bottom line is that I got all of the speed improvements I was looking for just by upgrading to a 32bit board with 24V power supply. The use of PETG instead of PLA in strategic places also allows motors to run fairly hot (1.5A out of the rated 1.8A) without worrying about motor mounts melting 
Like with everything in life, more speed would certainly be merrier, but given the amount of $ that went into this, there’s hardly any reason to not be as happy as a clam about these numbers.